In my module to trait correlations analysis with WGCNA I find significant correlations in several cases. I do however also see correlations with the grey module is the range of about 0.5 - 0.6. The grey module consists of 8390 genes out of the total 14729 in my dataset. This leads me to belive that there is an overall correlation between the dataset and the traits. If this is the case then would in be more interesting to see which modules have the opposite correlation to that of the grey module and a specific trait?
Is this a correct assesment and how should I be thinking about this -- is there anything Im missing?