Protein TMT data; Dispersion plot looks strange

Question

[BS]

https://1drv.ms/b/s!AgjiBVqYkILZg7sS9Bavf_-6YPEYLg?e=1xDxkK

Kindly go through the image. I am using DESeq2 to analyse protein TMT data. I get the differentially expressed proteins. However, the dispersion plot looks strange. Does that mean that DESeq2 cannot be used to analyse the data? Note that I did not normalise similar to the libary normalisation done for RNASeq study.

Thanking you in advance for any suggestions and comments.