Entering edit mode
5.0 years ago
seta
★
1.9k
Dear all,
I analyze the genetic variation association with a given quantitative trait using PLINK. As I found, this tool reported a beta coefficient per one minor risk allele; so, this value (beta) will be multiplied in 2 for the individuals with two minor risk alleles, yes? However, the beta value of two risk alleles can not be exactly two-fold of one risk allele even under the additive model, isn't it?
Any comments would be highly appreciated
