I want to do an integrated analysis between the expression(transcriptome data) and mutation of 14 proteins and will use ICGC data to achieve this aim. But as you know the ICGC doesn't have proteome data. How can I correlate between the expression and transcription of those proteins without any proteome data and wet lab analysis? Does it necessary?
If there is no way to correlate between them, will my findings be acceptable in terms of science?