Question: What is a HaploContig
0
gravatar for afollette
5 weeks ago by
afollette0
afollette0 wrote:

Hey everyone,

I've been seeing the word haplocontig used when referencing de novo assembly pipelines. I believe I understand what a contig is, the combination of a group of reads that overlap without gaps. However, what nuance makes a normal contig a haplocontig?

Thanks!

haplocontig • 77 views
ADD COMMENTlink modified 5 weeks ago by lieven.sterck10k • written 5 weeks ago by afollette0
2
gravatar for lieven.sterck
5 weeks ago by
lieven.sterck10k
VIB, Ghent, Belgium
lieven.sterck10k wrote:

from the top of my head: that would indicate a contig that is assigned to a specific haplotype. This is a somewhat new given, linked to the fact people are now doing haplotype aware assemblies (were back in the days we nearly all did consensus of haplotype assemblies) and where thus both haplotypes are being assembled as separate entities.

haplocontigs thus represent the same genomic region but from different haplotypes (you can see it a bit as allelic contigs)

ADD COMMENTlink written 5 weeks ago by lieven.sterck10k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1107 users visited in the last hour
_