Where Can I Find These Data?

Question

[atoogoe]

Folks!

Where can I find public repositories that contain good data for each of the following?

1. SNP-alleles to gene-expression
2. gene-expression to protein-levels

Your help would be very much appreciated. Thanks.

-Ato

[Luke]

I've recently become very interested in the correlation between RNA levels and protein activation (indeed, there doesn't seem to be any), and found some evidence for a low correlation (R<0.4) for any given RNA~protein association - but this review looked at 10 studies (4 cell lines, 6 human in-vivo studies) of specific genes. If there is indeed a database on the expected/observed relationship between RNA and protein, that would be a very valuable resource.

[atoogoe]

Hi luke,

Can you provide a link or title of the review you mentioned in your comment? Thanks

[Luke]

Hello. The review I am referencing is unpublished (although the author, Nancy Kendrick, does intend on publishing shortly). http://www.kendricklabs.com/WP1_mRNAvsProtein.pdf

[atoogoe]

Thanks for sharing, Luke.

Answer 1

[ff.cc.cc]

I suppose you refer to eQtl database in point 1), if so this post is a good starting point.

Summary:

1) Pritchard lab at Chicago

2) GTEX at NCBI

3) Genevar

4) SCAN DB

Sorry, but I'm not aware of repository about 2)

[atoogoe]

Eternal gratitude!