how to deal with large matrix for heatmap?

Question

[BioInProg]

Hi everyone! I have gene expression data for a cell line. The dimension of the data is about 800 rows (genes) * 2500 columns(therapeutics). What do you think my approach should be to create a heatmap?

Thanks in advance!

[ATpoint]

What exactly do you want to know? I see nothing generally forbidding such a heatmap. In scRNA-seq and similar assays one routinely creates HMs with thousands of columns and hundreds/thousands of genes. Check the ComplexHeatmap package for example.