Why the result of GSEA and ssGSEA is different?
0
1
Entering edit mode
19 months ago
Raheleh ▴ 230

Hi all, I have microarray data of two conditions.

When I did GSEA using fgsea the signature/ geneset was significantly higher in group1 vs group2.

However, when I did ssGSEA and used boxplot to show and assess significancy, that signature it is not significantly enriched in group1?

Can anyone told me how it can be explained? When you would use either approach?

Many thanks!

ssgsea gsea • 418 views
ADD COMMENT

Login before adding your answer.

Traffic: 1135 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6