Is it possible to call variants using cram files?
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7 months ago
vinayjrao ▴ 200

Hi,

I am working with some whole exome data, which was received as cram files. I am facing some problems converting the cram files to either bam or fastq. I would like to know if anyone has tried to remove duplicates and call variants from the cram file. I am certainly going to give this a shot regardless, but I would like to be careful of any intricate changes that need to be made in order to achieve this.

next-gen sequencing SNP • 310 views