Question: Population Mutation Rate And Zygosity
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gravatar for jackuser1979
8.2 years ago by
jackuser1979870
US
jackuser1979870 wrote:

I have identified frequency of SNPs, heterozygotes and homozygotes per 100kb for my eukaryotic species (which is maintained for 100 generations by inbreeding) by readmapping illumina paired-reads to reference genome. From Drake et al. Genetics, 1998, it is inferred that fixed mutations for eurkayotes (mutation rate are measured in substitutions) is 0.003 mutations per genome per generation. Can I use this for mutation rate calculation for of my eurkaryotic species?. How can I correlate my mutation rate to zygosity?

I also came across this tool:http://guanine.evolbio.mpg.de/cgi-bin/mlRho/mlRho.cgi.pl for estimating population mutation.

ADD COMMENTlink modified 8.2 years ago • written 8.2 years ago by jackuser1979870

Your question is very hard to understand. Do you want the population mutation rate (Theta)? Perhaps rephrasing your question would help here...

ADD REPLYlink written 8.2 years ago by Zev.Kronenberg11k
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