How To Find Functional Evidence For Multiple Gwas Loci?

Question

[foxylady]

Hi! Any tips on how to gather as much information about a given GWAS association signal as possible? I'm not interested in phenotypes, just evidence of functionality e.g. cis-eQTL, pathway enrichment, functional studies, annotation categories etc. I haven't yet stumbled over a database that gathers this information... Thanks in advance! K

Answer 1

[Dan]

These kinds of question are too specific to be answered by a single database (if I understood correctly). You'll have to gather information yourself, but there are algorithms to help you do it. e.g. http://www.ncbi.nlm.nih.gov/pubmed/16485021 (not the example I was thinking of, but somewhere to start).