I am trying to understand the evolution of a protein domain by constructing Phylogenetic tree and by analyzing its last common eukaryotic ancestor (LCEA). I obtained the homologs by blast search, then used Muscle for MSA and FastTree (since number of sequences is >1000, PhyML was too slow) to construct the phylogenetic tree. I am wondering if it is the right way to go. I am willing to know how to interpret the tree, find out the LCEA and explain how the protein has evolved. Thank you.
Question: Constructing Phylogenetic Tree And Analysing Evolution Of A Protein
7.7 years ago by
Pappu • 1.9k
Pappu • 1.9k wrote:
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