Question: Constructing Phylogenetic Tree And Analysing Evolution Of A Protein
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gravatar for Pappu
7.7 years ago by
Pappu1.9k
Pappu1.9k wrote:

I am trying to understand the evolution of a protein domain by constructing Phylogenetic tree and by analyzing its last common eukaryotic ancestor (LCEA). I obtained the homologs by blast search, then used Muscle for MSA and FastTree (since number of sequences is >1000, PhyML was too slow) to construct the phylogenetic tree. I am wondering if it is the right way to go. I am willing to know how to interpret the tree, find out the LCEA and explain how the protein has evolved. Thank you.

python phylogenetics • 2.1k views
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