I have 100 samples (individuals) and 100 (SNPs) genotyped. I call the SNPs either a WildType (WT) or a Rare-variant (RV) across all samples. Few SNPs in a sample had very poor quality. So It is a missing value. I read in this case/control information as matrix. How do we read the missing value in DEXSeq analysis ??? Should I set them to '0' or just leave it blank?