Question: Dn/Ds For Correlations - Data Normalization
1
gravatar for jprmachado
7.6 years ago by
jprmachado60
jprmachado60 wrote:

I have a dataset with lots of dN/dS values coming out from PAML, my question is how can i normalize the data for parametric correlations? Most of values fall between 0 - 0.1.

data codeml statistics • 2.3k views
ADD COMMENTlink modified 7.6 years ago • written 7.6 years ago by jprmachado60
3
gravatar for Michael Dondrup
7.6 years ago by
Bergen, Norway
Michael Dondrup48k wrote:

There was a very similar question yesterday: Normalising tag count to RPKM. The input data were different but both boil down to the same misconception: that normalization is always required. For calculating correlation it is irrelevant if the data is normalized (as long as the normalization function is monotonous). So the answer is no normalization is required, and non-parametric correlation might be preferred, because the data might not be normal.

ADD COMMENTlink modified 7.6 years ago • written 7.6 years ago by Michael Dondrup48k

Hi Michael,

Thank you for the explanation. I have made a search and didnt found anything with my keywords.

I think this topic can be close. Thanks,

João

ADD REPLYlink written 7.6 years ago by jprmachado60
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