Question: Is It Necessary To Remove Duplications After Bwa Alignment?
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gravatar for Tonyzeng
5.5 years ago by
Tonyzeng300
Tonyzeng300 wrote:

HI, I got another question here, is it always necessary to find duplicates and remove them after bWA alignment whatever alignment is good or not?

bwa • 2.3k views
ADD COMMENTlink written 5.5 years ago by Tonyzeng300

see that thread on SE: http://seqanswers.com/forums/showthread.php?t=6854&highlight=large+sample+calls

ADD REPLYlink written 5.5 years ago by Pierre Lindenbaum119k

Pierre has been too gentle. I would suggest that you first use the search function here looking for "duplicates" or for "markduplicates", and also to use the "tags" section selecting any of those 2 mentioned tags. you'll find plenty of information there that describes what NGS duplicates are, why we have to consider them specially in the analysis, when it's advisable to remove them and when it's not,...

ADD REPLYlink written 5.5 years ago by Jorge Amigo11k
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