Job:Two postdocs (one wet, one dry) in 3' UTR biology and RNA threapeutics
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20 days ago

Are you a bioinformatician or computational biologist or molecular biologist with a passion for RNA, gene-regulation, synthetic or systems biology or biotechnology? Do you want to be part of a team delivering genuinely useful innovation? The Sudbery and Wilson labs in the Department of Molecular Biology and Biotechnology at the University of Sheffield, in collaboration with AstraZeneca are looking to recruit two Research Associates to work on an MRC funded project creating synthetic UTR sequences for use in RNA therapeutics. You will form the part of a team comprising 3 Research Associates (two academic and one industrial) and a PhD student.

You will have a PhD in an appropriate subject and a research record in either bioinformatics, computational biology or molecular biology. You will be able to demonstrate a collaborative mindset, that you are always looking to acquire and use new skills and enjoy working in an interdisciplinary way and interacting with external partners. You will look forward to being part of a community of researchers working towards common or related goals and be looking forward to helping foster such a community.

The project will involve using the latest in high-throughput molecular and synthetic biology techniques, statistical analysis and machine-learning to understand the grammar of RNA stability and translation regulation by the 3’ UTR and apply this knowledge to create sequences for AstraZeneca to use in their RNA therapeutics platform, including their Pandemic Prevention Program (P3). You will be responsible for the delivery of the either the lab or computational part of the project but will collaborate closely with other team members. Both positions will require close working with the other, and a keeness to help learn something of what the other does and help out occasionally.

The Sudbery (www.sudlab.co.uk) and Wilson labs are part of the Sheffield Institute for Nuclei Acids (genome.sheffield.ac.uk) and the Department of Molecular Biology and Biotechnology, internationally recognized for its excellence in biology research. Biology research at Sheffield was ranked 1st in Biomedical Sciences Allied to Health and 5th in Biology Sciences in the 2014 REF.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

To find out what makes the University of Sheffield a remarkable place to work, watch this short film: www.youtube.com/watch?v=7LblLk18zmo, and follow @sheffielduni and @ShefUniJobs on Twitter for more information.

Apply for the Dry lab/computational job here

Apply for the web lab job here

rna machine-learning utr • 116 views
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