Rare cell population in single cell ATAC-Seq
1
0
Entering edit mode
20 days ago
ahmad mousavi ▴ 530

Hello guys,

I am working on a single cell ATAC. I am wondering to know, is it possible to find small/rare population in single cell ATAC-Seq era which are not found in bulk ATAC-Seq ?

I mean for sure the idea of single cell helps to find out the heterogeneity but has impact on depth and input cells.

Also, can we use deconvolution methods on ATAC as well?

Thanks.

atac-seq atac • 123 views
ADD COMMENT
1
Entering edit mode
20 days ago
heskett ▴ 60

Yes this is possible. There's now likely hundreds of research papers that use single cell ATAC seq to do exactly this task, if you read maybe 5, you will begin to get an idea of what methods they use and what kind of results are possible.

ADD COMMENT

Login before adding your answer.

Traffic: 2350 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6