Non-european ancestry in eQTL analysis
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15 months ago
Colari19 ▴ 90

What is the best way to deal with non-european ancestry in eQTL analysis?

We have matched RNASeq and genotype data for 85 subjects, 21 of which show evidence of non-european ancestry.

It seems a common approach is to discard such samples, but this seems wasteful. Can this be dealt with by including genotype principal components in the analysis?

Thank you.

gwas eqtl • 332 views
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Cant you pool them and run it in a multi-ethnic fashion?

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