VEP Disk Space
1
0
Entering edit mode
5 months ago

Hello,

I want to annotate VCF-files with VEP and want to use the CADD-plugin. This I want to do on a local computer (1 TB SSD/64GB Ram). My question ist, how the data for VEP annotation is stored? Is e.g. ALL the CADD-Data for the entire genome stored on my local computer? Or in easier words...does installing VEP + CADD need large disk space and is not feasible on local computers?

Best, Andreas

VEP Ensembl • 197 views
ADD COMMENT
3
Entering edit mode
5 months ago

The GRCh38 release 103 VEP cache on my machine (domestic Mac, no cluster) is 17 GB. The unannotated CADD file from here is 81GB.

ADD COMMENT

Login before adding your answer.

Traffic: 1748 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6