Recently, I wished to use MutSig2CV_NC software link for the noncoding mutational analysis, which required me to provide a unique patient identifier. The fields required for the MutSig2CV_NC are listed below,
chr, pos, patient, ref_allele, newbase
However, I found that some specific patients may have multiple samples. The mutation data looks like this,
My question is how should I deal with these mutation data from different samples of the same patient.
Are there any tools, pipelines, or tutorials to merge or deal with these mutation data?
Thank you for your time!
I am looking forward to your answers. Any questions, just feel free to comment.