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2.9 years ago
manjumoorthy95
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60
I have downloaded the TCGA dataset for ACC Cancer type from RNAseqV2 data. In the level 3 files for the RSEM rnaseq data, the barcodes for the samples are given as follows : "TCGA-OR-A5J1-01A-11R-A29S-07".
How to understand whether the sample is tumor or normal? In here, TCGA description for barcode , the barcode explained is given in different manner. Any help would be appreciated.
But all the samples in the dataset has “01A” in the barcode. When we search in the GDC portal, they have reported that in TCGA-ACC, there does exist Normal Tissue samples as well.
You might be referring to blood normal samples which only undergo DNA-seq because their RNA-seq is not relevant to tissue-specific gene expression. From querying for "solid tissue normal" in TCGA ACC on GDC, I only see two cases, and they don't have RNA-seq. I can confirm the same in the legacy GDC archive.
If you are seeking normal gene-expression in adrenal gland tissue, look into GTex instead of TCGA.