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3.0 years ago
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Hello
Is there any rule of thumb for filtering shrunken logFC, similar to |logFC|>1.5 for raw results? Or perhaps one should find the cutoff purely based on the distribution of shrunken logFC? I think some standardized value is needed though, e.g. from the perspective of volcano plots.
Kind regards
I think this question was answered so many times here. You need to determine a threshold depending on experimental setup, type of experiment, biological questions.. shrunken logFCs have nothing different (in term of how to manage them) than non-shrunken logFCs.
I tried to find the answer on the forum but couldn't find one. Please be more specific.