Allele frequency for genes
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5 weeks ago
luffy ▴ 20

Hello All,

Where can i find allele frequency cut offs (or upper and lower range) for all the genes (for all the types of variants) to call variants polymorphic or rare in nature?

Thank you for your time

frequency gnomAD gene allele • 279 views
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You can google for "rare variant allele frequency"

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Thank you for you response, Yes, that would give a general (<1%) or some specific papers. I want it like for all genes and i know that its not same for all genes. If you check gnomAD constraint file they have provide ratio of observed and expected for each gene. I need a file like that from a reliable source for all gene. any idea about this? Thank you for your time

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It is the same for all genes. Oe score in GnomAD is not about the allele frequencies.

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Oh!! This calculator data is what I want for all gene. Or any similar data for which I can filter variants to be considered for pathogenicity

Thank you for your time

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