In time series I am confused about some definitions
In DESeq2 tutorial
library("fission") data("fission") ddsTC <- DESeqDataSet(fission, ~ strain + minute + strain:minute)
Can somebody please tell what this mean
The following chunk of code performs a likelihood ratio test, where we remove the strain-specific differences over time. Genes with small p values from this test are those which at one or more time points after time 0 showed a strain-specific effect. Note therefore that this will not give small p values to genes that moved up or down over time in the same way in both strains.
ddsTC <- DESeq(ddsTC, test="LRT", reduced = ~ strain + minute) resTC <- results(ddsTC)
Am I right that means only we will have genes related to the difference of strains and we removed genes related to changing over time??