high missing rate for genome data converted from impute2 output
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2.1 years ago
1311703846 • 0

hey guys, I found snps will lost genotype data after my data was converted from impute2 output to vcf using plink, because the equally probability between different genotype for a snp in specific indivudual. for example : if genotype for a snp is ( 0.5,0.5,0 ) in impute2 output for a person, then genotype for this snp will be ./. after converted to vcf using plink. what can i do to solve this problem? thanks for your help!

gwas impute • 416 views
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2.1 years ago
1311703846 • 0

I found the anwser for my question :) Because there is a hard-call-threshold option in plink which control the the operation of convert.

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