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24 months ago
tolers
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Leidos Public Health Division is seeking a number of Bioinformatics Developers to support public health projects. The ideal candidate will have demonstrated experience in Next Generation Sequencing (NGS) data analysis including development and application of quality control, assembly, functional annotation, sequence alignment, variant detection, and phylogenetic analyses of viral, bacterial, fungal and protist genomes, transcriptomes and metagenomes. This position is open to telecommuting, location preferred Atlanta.
Responsibilities
- Develop, test, and deploy bioinformatics data pipelines and workflows using open source platforms such as Agave, Nextflow and Taverna
- Develop and execute bioinformatics algorithms and workflows in high-performance computing environments; including cloud and hybrid-cloud execution environments
- Write customs scripts and software to perform bioinformatics analysis using Python, Perl, R and/or Java
- Perform bioinformatics analysis using open-source bioinformatics tools as well as licensed proprietary software such as CLC Genomics Workbench and Geneious. Support modeling and simulation of evolutionary and population biological process using Bayesian inference and/or genetic algorithms.
- Use statistical analysis tools, interpret and communicate results
- Develop tools for visualizing complex biological datasets and able to interpret and communicate results as well as uncertainty to a diverse group of customers.
- Develop and maintain highly curated genomic sequence databases, signature databases for virulence and AMR markers, strain type and pathogen type markers.
- Work together with the DevOps team in adopting best software engineering practices for tool and workflow development.
- Adapt bioinformatics algorithms and workflows in high-performance computing environments; including cloud and hybrid-cloud execution environments.
- Provide guidance and support in scaled data analysis and management of next generation metagenomic sequencing data.
- Assist with developing standard operating procedures for bioinformatics analyses.
- Support and maintain relational databases (MySQL/PostgreSQL) as well as NoSQL databases (MongoDB).
- Supports researchers in creating and submitting publication and poster presentations.
- Communicate progress orally and in writing with our scientific community stakeholders
- Assist with preparation of reports, presentations and papers for publication in scientific journals, conferences and meetings
MINIMUM QUALIFICATIONS
- A master's degree in bioinformatics, genomics, molecular biology, genetics or related field;
- 3+ years of bioinformatics experience
- Experience in front-end development for bioinformatics tools, workflows and applications using AngularJS and NodeJS.
- Experience with processing of high-throughput data and possessing strong data management and analysis skills.
- Experience working in Linux environments and broad experience with open source bioinformatics tools
- Proficient coding/scripting in Python, R, Perl
- Experience working in a high-performance computing and/or cloud computing environment
- Competency writing customs scripts and software to perform bioinformatics analysis using Python, Perl, R and/or Java.
- Strong communication skills
- Ability to obtain NACI clearance.
PREFERRED QUALIFICATIONS
- Strongly preferred experience in operating and developing components for workflow management systems such as Nextflow, Snakemake, and/or Workflow Description Language (WDL).
- Experience in one or more of the following phylogenetic analysis and visualization tools is highly desirable: BEAST, FastTree, RaxML, TreeTime, NextStrain, Microreact
- Experience in designing and conducting training workshops to the bioinformatics community on latest bioinformatics methods and concepts.
- Experience with Tableau, Cloudera (Hadoop), JavaScript
- Experience with machine learning approaches
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