gProfiler: Customising the gostplot

Question

[anand.gururajan]

Hi all.

I'm wondering if it's possible to customise the gostplot produced by gProfiler to only include GO:MF, GO:CC, GO:BP and KEGG. I'm not interested in the others like REAC, TF or CORUM. The manual doesn't seem to provide an option to exclude whole categories.

Thanks.

[antonioggsousa]

Hi,

It depends if you're using the the online interface (https://biit.cs.ut.ee/gprofiler/gost) or the API. In any case, a simple workaround is just select the databases that you're interested in (if you're using the online interface, under the field Data sources): GO:MF, GO:CC, GO:BP and KEGG. Actually, if you're only interested on these, I think you even should only select this to start with, since you're more likely to get more hits, since the multiple testing correction will be apply across less terms/pathways.

I hope this helps,

António