chromosome location to gene name and aa change

Question

[Zi]

Hi, I have just found an annotation metric, which contains data in these columns,

CHROM : chromosome
POS : position
REF : reference nucleotide
ALT : alternate nucleotide
hspred : "high sensitivity" prediction for exome analysis
pred : prediction for global performance

and I want to use these metrics for my list on snps in several genes, therefore I wonder how can I convert these chromosome coordinates to gene names and corresponding aminoacid changes in python preferably.

Thank You

[Pierre Lindenbaum]

search this site for snpeff vep, etc...