We seek an ambitious candidate who is interested in applying their skills at the interface of human disease and genetics. The appointed Research Scientist will be embedded in an interdisciplinary team of neuroscientists, bioinformaticians, statisticians, geneticists, and computational biologists.
The CDR studies the molecular, cellular, and genetic mechanisms underlying neurodegenerative and neuropsychiatric disorders including Alzheimer's disease, Alzheimer's disease related dementias, schizophrenia, and bipolar disorder, among others.
Distinguishing features of our research are the generation of large-scale ‘omics data in human brain tissue, including epigenomics and transcriptomics and the use of genome sequencing for big data integration. As part of the CommonMind Consortium (https://www.synapse.org/cmc) and PsychENCODE Project (https://www.synapse.org/pec), we are generating multi-scale ‘omics data in human brain tissue that involves multiple brain regions and cell types, clinical diagnoses and developmental stages.
The ideal candidate will work under direct supervision of senior staff and assist with the bioinformatics components of numerous developing and ongoing projects. Excellent opportunities exist to train and to understand and integrate relevant biological concepts of applied bioinformatics. Room for scientific growth, career enhancement and development into an independent investigator in academia.
Responsibilities include but not limited to:
- Analyses of high throughput genomic, transcriptomic, epigenetic, proteomic, digital spatial, and other 'omics data in healthy and disease states.
- Analysis of multiscale single cell ‘omics data to perform multi tissue cellular de novo taxonomy in healthy and disease states.
- Develop and maintain genetic, genomic, and biological databases to annotate and interpret human genome data.
- Perform rigorous and reproducible data analyses along with graphics and spreadsheet output.
- Develop projects and work independently on a variety of data analysis projects.
- Learn and use bioinformatics tools for processing and analysis of large datasets.
- Identify and resolve technical issues and propose upgrades to current software.
- Develop and maintain bioinformatic pipelines for analyses of high throughput genomic, transcriptomic, epigenetic, proteomic, and other 'omics data in healthy and disease states
Job qualifications:
Minimum:
- Ph.D. in Bioinformatics, Computational Biology, Computer Science, Biomedical Engineering, Computer Engineering, Genetics/Genomics or related field.
- Experience with ‘omics platform output.
- Experience with biological datasets and next generation sequencing data.
- Graphical output of data analysis for publication.
Preferred Qualifications:
- Demonstrated experience designing computational methods and tools, including prior experience with algorithms relevant to computational biology, and skill and experience with statistical analysis.
- Outstanding programming skills in at least two of these languages on a Linux environment: Python, R, bash, Perl, Java, and C++.
- Excellent communication and organizational skills with ability to work to tight timelines, both independently and as part of a multi-disciplinary team.
Location: The internationally recognized CDR at the Nathan Kline Institute for Psychiatric Research, an affiliate of NYU Grossman School of Medicine, located 15 miles North-West of the GW Bridge on the campus of Rockland Psychiatric Center, Orangeburg, New York.
Interested candidates should apply here (https://statejobs.ny.gov/public/vacancyDetailsView.cfm?id=139367) and submit their resume with filled application to employment@nki.rfmh.org.
