Hi all,
To identify remote homology, I have used different tools using benchmark dataset for which I have the labels for the true homologs. I have calculated the AUC values based on True positives and False positives in the homology result for each classifier.
The AUC values for different classifiers are like this
Classifier 1 -0.601
Classifier 2 - 0.732
Classifier 3 - 0.752
Classifier 4 - 0.828
Classifier 5 - 0.883
What is the best way to assign weights to each classifier (as they have different performance) so that I can multiply these weights to the normalized scores of each individual tools to find the aggregated score?
Thanks in advance
Thanks for your answer. I am interested in giving weights to each tool that I have used for detecting the homologs for my query proteins as stated in "https://www.nature.com/articles/srep32333#Sec6".
I am unable to find that how are they assigning weights to each tool.