Entering edit mode
6 months ago
mropri
▴
150
Hi,
I just want to understand first, when you put confounders in your DESeq object model, are they regressed out or just accounted for. Second, why is the nbinomwald test used when in DESeq2 is already is getting you log2 fold changes with p values using DESeq2(dds) which also accounts/regresses out for you confounders in your model that you put when creating the DESeq2 object. Hope my question was clear and would appreciate any help. Thank you