I am conducting a study which involves the comparison between more than 3 experimental conditions. In particular, I would like to study the methylation status of samples and to find differentially methylated regions between these conditions. Let's say if I only have bisulfite-seq data for one of these conditions but have found bisulfite-seq datasets in the public for the other two conditions, can I analyse them together and potentially find some "real" DMR regions between them?
Potentially, I am also looking to evaluate the genomic differences between these conditions. Is WGS data also comparable between different studies?