Dear community members,
not exactly bioinformatic question, but as a bioinformatician I simply don't have accounts at purely biological boards,
I see that a long exon of one particular human disease causing gene is often targeted by mobile elements of different families (LINE1 and ALU) at different positions - so seems that the whole exon is vulnerable.
It happens at a rate certainly higher than random. The question: why?
As a bioinformatician, of course the first thing I thought is "there should be some specific motif" - but how to find such a motif + the insertions happen at different positions.
Which epigenetic data could help to establish the vulnerability of this exon?