Entering edit mode
8 months ago
piotto
▴
20
I did an analysis via CellPhoneDB (CPDB) package and I am wondering how can I limit the results to cell surface proteins?
This is the dats's head:
> colnames(cpdb)
[1] "id_cp_interaction" "interacting_pair" "partner_a" "partner_b" "gene_a"
[6] "gene_b" "secreted" "receptor_a" "receptor_b" "annotation_strategy"
[11] "is_integrin" "Interacting_cell" "Relevance" "Cell_a" "Cell_b"
[16] "Mean" "Zscore" "Mean_scaled"
> head(cpdb, n=1)
id_cp_interaction interacting_pair partner_a partner_b gene_a gene_b secreted receptor_a receptor_b
1 CPI-SS0DE0A486F NRP1_VEGFA simple:O14786 simple:P15692 NRP1 VEGFA TRUE TRUE FALSE
annotation_strategy is_integrin Interacting_cell Relevance Cell_a
1 curated FALSE Fibroblast_Cluster 1|Fibroblast_Cluster 2 0.749 Fibroblast_Cluster 1
Cell_b Mean Zscore Mean_scaled
1 Fibroblast_Cluster 2 0.749 -0.000276821 0.3723209