Issue with bigWigSummary utility of Kent/UCSC utilities

Question

[eeb74]

Hi, I am trying to compute the average enrichment of signal across a region of bins from a deepTools computeMatrix output. In trying to do this, I came across this Google Groups post recommending to use the bigWigSummary tool of the Kent/UCSC utilities:

https://groups.google.com/g/deeptools/c/xnNq_5l5IQ8

I am having trouble running this though and have not found good documentation for this tool to base my syntax off of. Has anyone on here used the bigWigSummary tool to do this kind of analysis? Would you be able to provide an example script? Thank you in advance for your help with this!

[Pierre Lindenbaum]

I am having trouble running this though and have not found good documentation for this tool to base my syntax off of.

show us the command line

and have not found good documentation

https://hgdownload.soe.ucsc.edu/admin/exe/linux.x86_64/

### kent source version 362 ###
bigWigSummary - Extract summary information from a bigWig file.
usage:
   bigWigSummary file.bigWig chrom start end dataPoints
Get summary data from bigWig for indicated region, broken into
dataPoints equal parts.  (Use dataPoints=1 for simple summary.)

NOTE:  start and end coordinates are in BED format (0-based)

options:
   -type=X where X is one of:
         mean - average value in region (default)
         min - minimum value in region
         max - maximum value in region
         std - standard deviation in region
         coverage - % of region that is covered
   -udcDir=/dir/to/cache - place to put cache for remote bigBed/bigWigs