Best way to add alter fastq file by adding short repeats

Question

[pairedttest]

Hi there

I am currently working on building a tool to detect STRs in fastq files. I want to generate a dummy fastq file with a known number of 4bp repeats so that I can see if the tool actually works. what is the best way of doing this? I was thinking of just copy-pasting it into the fastq file manually, but that seems less than ideal. does anyone know of any way this could be accomplished?

thanks

[GenoMax]

You could also get real data referenced in this publications (and others noted); https://pubmed.ncbi.nlm.nih.gov/26722765/ and https://www.frontiersin.org/articles/10.3389/fmolb.2023.1093519/full