Minimum number of samples for multi-omics data integration

Question

[Tundup]

Hi!

I am new to multi-omics data integration. I want to know what should be the minimum number of samples (with 2 omics and clinical data, meta data) for integration?

I am also going to apply ML algorithms on integrated data to find biomarkers.

How one should some up with this before doing the integration? I am planning to set the sample size before sample collection.

[manaswwm]

If your analysis is aimed at comparing two groups (eg: treatment conditions), then you should probably have a look at power calculations to see what would be the statistically ideal sample size