Herald:The Biostar Herald for Thursday, October 23, 2025
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The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here.

This edition of the Herald was brought to you by contribution from Istvan Albert, and was edited by Istvan Albert,


Indexing and searching petabase-scale nucleotide resources | Nature Methods (www.nature.com)

Searching vast and rapidly growing nucleotide content in resources, such as runs in the Sequence Read Archive and GenBank, is currently impractical [...] Here we present Pebblescout, a tool that navigates such content by providing indexing and search capabilities.

submitted by: Istvan Albert


Petabase-scale sequence alignment catalyses viral discovery | Nature (www.nature.com)

Here we developed a cloud computing infrastructure, Serratus, to enable ultra-high-throughput sequence alignment at the petabase scale.

submitted by: Istvan Albert


Efficient and accurate search in petabase-scale sequence repositories | Nature (www.nature.com)

We present MetaGraph, a methodological framework that enables us to scalably index large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.

submitted by: Istvan Albert


The AI coding trap | Chris Loy (chrisloy.dev)

Software development is fundamentally a practice of problem-solving, and so, as with solving a tricky crossword, most of the work is done in your head. [...] but with AI-driven coding, things play out very differently.

submitted by: Istvan Albert


Ten years of genomics at Google (blog.google)

A look back at a decade of research in genomics at Google, from developing AI tools that accurately read the code of life, creating comprehensive reference genomes and working with partners on real-world challenges from biodiversity to healthcare.

submitted by: Istvan Albert


Choose your human genome reference wisely | Nature Methods (www.nature.com)

Scientists can choose between multiple human genome references, and a pangenome reference is coming. Deciding what to use when is not quite straightforward.

submitted by: Istvan Albert


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