Entering edit mode
9.0 years ago
miquelduranfrigola ▴ 770
I have a list of UniprotACs corresponding to enzymes (no structure available for most of them). I'd like to identify residues in the active site. For now, I am looking at InterPro and extracting regions with the tag "site". Is this good practice? Any better option?
Many thanks in advance,
If the list is small, you can do homology modeling and look at cavities + key residues. (or) atleast for few you can do a sanity check to see if the regions you had extracted resembles an active site in a model.