TopGO: Select significant terms under a parent GO term

Question

[QVINTVS_FABIVS_MAXIMVS]

After running signifance tests on my GOdata, I want to select all the significant GO terms under a parent GO term, which is not significant.

If the parent term is GO:0008152, I want to select all significant child GO terms such as GO:0006521

Answer 1

[biotech]

Method

• install 'ONTO-PERL' module:
• follow README file
• download 'OBO' file -> http://www.geneontology.org/GO.downloads.ontology.shtml

• Example: run 'ONTO-PERL' script to get all descendants of GO term 'membrane' GO:0016020

  get_descendent_terms.pl gene_ontology_ext.obo GO:0016020 | wc -l 802

  get_descendent_terms.pl gene_ontology_ext.obo GO:0016020 > GO0016020.txt

Refrences:

Parsing Obo File