I got this via email from the EcoCyc mailing list. If you use EcoCyc tools, it would help them very much right now for you to write up a letter of support for them.
EcoCyc received a very unfavorable grant review in February 2014. We are in discussions with the NIH to resolve this situation.
EcoCyc's usage has steadily increased. We made very strong progress on our challenging aims from the current grant period, and the project has produced many publications. EcoCyc received excellent reviews on previous grant applications. Furthermore, the needs of the prokaryotic research community for the content and software tools offered by EcoCyc have never been higher.
In the worst case, we will lose all funding on July 1, 2014 and be forced to re-apply. Even in the best case, we may receive a crippling funding cut that causes the project to fall behind in its manual literature curation effort, and requires us to lay off our experienced curation staff until continued funding can be obtained.
These events could seriously undermine EcoCyc, end the project altogether, or force us to begin charging usage fees.
(I am not affiliated with EcoCyc, just want to support them)