gravatar for chevivien
6.0 years ago by
chevivien70 wrote:

Could anyone suggest to me a bioinformatics software for identifying SNP in plant gene families? For example if one has number of a particular gene family say HSP and I wanna know if SNP has any direct or indirect effect on its functionality in plants,which bioinformatics tool is suitable for this kind of analysis? 

I have seen a number of tools for SNP analysis through google l search like SIFT and Polyphen but its more tailored to human genomes, is the tools like these tailored for plants genomes?

variant analysis snp plants • 1.8k views
ADD COMMENTlink modified 6.0 years ago by Josh Herr5.7k • written 6.0 years ago by chevivien70
gravatar for Josh Herr
6.0 years ago by
Josh Herr5.7k
University of Nebraska
Josh Herr5.7k wrote:

I cleaned up your question a bit to make it clearer to understand. Asking a clear question will get you a faster and more specific answer so it's a good idea to put some time into crafting your words and doing a little bit of background research first.

I'm not clear on exactly what you want to do a SNP analysis for -- I'm not sure you know either. Are you trying to tie a SNP to functional gene diversity? -- you'll probably need some laboratory experiments to back those conclusions up. Are you trying to use SNPs for phylogenetic hypothesis generation/testing?

Most of the tools for SNP analysis in humans also work in plants -- I've had to use many of them because I am unaware of any specific SNP tools for plants (except for this R package). My current SNP pipeline uses SnpEff/SnpSift for SNP detection. I'm also using CORTEX for assembly based variant calling.

There are many many questions here about SNP calling -- here's a few.

ADD COMMENTlink modified 9 months ago by RamRS27k • written 6.0 years ago by Josh Herr5.7k
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