How to identify whether this is pseudo gene or not?

Question

[mangfu100]

Hi.

I have found some gene containing variation. And then to further process, I want to know whether these genes are pseudo gene or not. It is because if detected gene is pseudo gene then, I don't need to further inspect it.

So Is there any well-known database to confirm pseudo genes?

[PoGibas]

This is great thread on "confirming pseudogenes": How To Predict Pseudogenes In A Genome

Answer 1

[Denise CS]

Ensembl annotates protein coding genes, ncRNA genes and pseudogenes. For human, mouse, zebrafish, pig and rat, Ensembl contains both automatic (with the Ensembl genebuild annotation pipeline) and manual annotation from the HAVANA team. You can check if these loci were annotated as pseudogene or otherwise.