Question: marker information for cancer that have been accessed by FDA
0
gravatar for J.F.Jiang
5.6 years ago by
J.F.Jiang820
China
J.F.Jiang820 wrote:

Hi all,

I am very interested in those markers with approved target drugs by FDA.

Although several webs gave out some summary for various cancers, genes, mutations, there seems no in hand table to include the format as follows,

cancer type-> gene-> HGVS mutation -> approved drug name

 

If anyone has this kind of source, it will be of great help if you can offer a share.

 

Best.

cancer fda marker • 1.6k views
ADD COMMENTlink modified 4.0 years ago by sue.mockus0 • written 5.6 years ago by J.F.Jiang820
0
gravatar for Bioinformatics_NewComer
5.6 years ago by
Genomic Island
Bioinformatics_NewComer320 wrote:

http://dgidb.genome.wustl.edu/

This is better than PharmGKB, I'd say. PharmGKB doesn't provide one-to-one mapping of drug and gene by default.

You will have to get your gene name and then select from the options at this website. There is a download section in this website, check that out.

Mainly [ on many websites], drugs are associated with the genes, and you will have to find genes of your interest.

I would be more than happy to find a source which has cancer type-> gene-> HGVS mutation -> approved drug name mapping.

 

 

 

ADD COMMENTlink modified 5.6 years ago • written 5.6 years ago by Bioinformatics_NewComer320

Thanks, DGI indeed offers us a catalog for cancer genes which have already been reported having target drug. However, like it's sources, it did not offer any information for markers, e.g., chrome and position, or HGVS info.

ADD REPLYlink written 5.6 years ago by J.F.Jiang820
0
gravatar for sue.mockus
4.0 years ago by
sue.mockus0
sue.mockus0 wrote:

Check out jax.org/ckb

ADD COMMENTlink written 4.0 years ago by sue.mockus0
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