Question: Tajima's D value interpretation
0
gravatar for rohan.pat.131191
4.2 years ago by
rohan.pat.1311910 wrote:

For my sequences I got Tajima's D value as -0.94880 and P > 0.10. I was wondering if I could use this results to claim that the test of neutrality is negative and the molecule under consideration is under selection pressure?

p value • 13k views
ADD COMMENTlink modified 7 months ago by gusa_100 • written 4.2 years ago by rohan.pat.1311910
6
gravatar for tlorin
4.2 years ago by
tlorin250
Switzerland
tlorin250 wrote:

I can't answer with more detail to your question, I'm sorry, but just FYI this is an excellent video on this topic :)

ADD COMMENTlink modified 2.5 years ago • written 4.2 years ago by tlorin250
3
gravatar for Giovanni M Dall'Olio
4.2 years ago by
London, UK
Giovanni M Dall'Olio26k wrote:

A negative Tajima's D value is usually interpreted as purifying selection, or as a signature of a recent population expansion.

You didn't explain how you calculated the p-value, so it is difficult to interpret it. It seems that it is higher than 0.10, so not significant. You should plot the distribution of Tajima's D on the rest of the genome (or at least the same chromosome), and see where your value falls.

ADD COMMENTlink written 4.2 years ago by Giovanni M Dall'Olio26k

I have calculated Tajima's d from Pairwise data and no of segregating sites. How to Normalize "d" valus into "D" manually as I have calculated my Tajima's d from character data and not sequence data.

ADD REPLYlink written 3.0 years ago by jigarnt30

Here we are having a conflict. While Tajima'D and Fu's are significant and negative, our BSP indicates a no recent event of population expansion but constant size. We used D-loop and ~1000 sample size for a single population. Do you know why this conflict ocurrs?

ADD REPLYlink written 7 months ago by gusa_100
0
gravatar for simar-coasab
3.1 years ago by
simar-coasab0 wrote:

what 'Tajima's D (NonSyn/Syn) ratio' tells?

ADD COMMENTlink written 3.1 years ago by simar-coasab0
0
gravatar for gusa_10
7 months ago by
gusa_100
gusa_100 wrote:

Here we are having a conflict. While Tajima'D and Fu's are significant and negative, our BSP indicates a no recent event of population expansion but constant size. We used D-loop and ~1000 sample size for a single population. Do you know why this conflict ocurrs?

ADD COMMENTlink written 7 months ago by gusa_100
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