Tajima's D value interpretation
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7.2 years ago

For my sequences I got Tajima's D value as -0.94880 and P > 0.10. I was wondering if I could use this results to claim that the test of neutrality is negative and the molecule under consideration is under selection pressure?

p value • 23k views
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7.2 years ago
tlorin ▴ 340

I can't answer with more detail to your question, I'm sorry, but just FYI this is an excellent video on this topic :)

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7.2 years ago

A negative Tajima's D value is usually interpreted as purifying selection, or as a signature of a recent population expansion.

You didn't explain how you calculated the p-value, so it is difficult to interpret it. It seems that it is higher than 0.10, so not significant. You should plot the distribution of Tajima's D on the rest of the genome (or at least the same chromosome), and see where your value falls.

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I have calculated Tajima's d from Pairwise data and no of segregating sites. How to Normalize "d" valus into "D" manually as I have calculated my Tajima's d from character data and not sequence data.

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Here we are having a conflict. While Tajima'D and Fu's are significant and negative, our BSP indicates a no recent event of population expansion but constant size. We used D-loop and ~1000 sample size for a single population. Do you know why this conflict ocurrs?

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6.1 years ago

what 'Tajima's D (NonSyn/Syn) ratio' tells?

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3.6 years ago
gusa_10 • 0

Here we are having a conflict. While Tajima'D and Fu's are significant and negative, our BSP indicates a no recent event of population expansion but constant size. We used D-loop and ~1000 sample size for a single population. Do you know why this conflict ocurrs?

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