Intron orders transcripts like encoded amino acid
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7.2 years ago
kevberm • 0

What are the prospects that seq derived from introns of a single gene transcript set order the transcripts in a similar way to the amino acid seq derived from transcript exons?

mRNA amino-acid RNA-Seq intron transcript • 1.4k views
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What exactly do you mean by "order the transcripts"? I assume you mean something like, "determines their transcription start/stop positions in the genome".

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7.2 years ago
kevberm • 0

From our initial compute efforts; signatures of sequenced protein, derived from multiple same gene transcripts order transcripts as expected. But, ordering transcripts by ‘ncRNA sequence signatures’ derived from intron sequences, for all combinations for a given sequence length surprisingly resembles transcript order by ‘protein sequence signatures’.

We think the relative transcript order may be a rank of ncRNA (hierarchical function) to the encoded protein

Any suggestions, thoughts etc.?

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