Question: Know Of A Database Of Disease Symptoms, Preferably Linking To Mesh Terms?
gravatar for Larry_Parnell
5.9 years ago by
Boston, MA USA
Larry_Parnell16k wrote:

Colleagues in our Computer Science department are developing a tool which identifies genes and medical terms taken from MeSH headings and its hierarchy (category C). I suppose that this in some way could be described as identifying co-morbidities and the responsible genes, but there are other things that they're also trying to solve.

I suggested that they also try to link the disease terms to symptoms whether they be external (eg, skin rash), invasive (eg, red blood cell count) or clinical (eg, results of a culture). However, no one present knew of a digital database linking symptoms to MeSH disease headings (category C), or anything similar.

Thus, we'd be grateful for any pointers or advice on this topic.

disease • 7.3k views
ADD COMMENTlink modified 8 months ago by Emre60 • written 5.9 years ago by Larry_Parnell16k
gravatar for Khader Shameer
5.9 years ago by
Manhattan, NY
Khader Shameer17k wrote:

Not exactly a database solution, but a set of terminologies related to clinical symptoms / clinical procedures / classification of diseases are routinely used in biomedical informatics projects like the one you explained.

These terminologies were already mapped or can be mapped to MeSH terms.

See manuscript describing mapping of SNOMED-CT to MeSH here and ICD-9 to MeSH here.

ADD COMMENTlink written 5.9 years ago by Khader Shameer17k

Thanks, Khader. I thought that you would have something to contribute on this topic.

ADD REPLYlink written 5.9 years ago by Larry_Parnell16k
gravatar for Alex Paciorkowski
5.9 years ago by
Rochester, NY USA
Alex Paciorkowski3.3k wrote:

You might also take a look at the Unified Medical Language System here, which includes MeSH. Often it also includes additional terms that are not found in MeSH.

Depending on your phenotypes, the Human Phenotype Ontology Website here may be useful.

ADD COMMENTlink written 5.9 years ago by Alex Paciorkowski3.3k

Thank you, Alex. These are good points to pass to my colleagues.

ADD REPLYlink written 5.9 years ago by Larry_Parnell16k
gravatar for Camwebb
5.6 years ago by
Camwebb10 wrote:

Thanks for this question (similar to this other linked thread). Please visit this post for one possible way to go ahead with an open, distributed database of diseases X symptoms. Collaborators welcome!

ADD COMMENTlink written 5.6 years ago by Camwebb10
gravatar for Emre
8 months ago by
United States
Emre60 wrote:

I am cross posting from my reply from another post. Have a look at the Human symptoms–disease network. All the disease-symptoms relationships identified from text mining on Pubmed meta data and mapped to MeSH are in the supplementary data set 3.

ADD COMMENTlink written 8 months ago by Emre60
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