Question: question about NIH Epigenome roadmap neural differentiation data
gravatar for weihsianghuang
5.3 years ago by
United States
weihsianghuang0 wrote:

I've been trying to find the histone modification/RNA-seq/DNA methylation data of the Epigenome roadmap project from

I can't find some of the data described in "Dissecting neural differentiation regulatory networks through epigenetic footprinting", which is the data from ES cell differentiate into Neuroepithelial, and then Early Radial Glial, and Mid Radial Glial cells.

According to the Nature paper they seemed to deposited all their data onto the roadmap website, can anyone help me to find them please? 


thank you






neuron roadmap epigenetics • 1.5k views
ADD COMMENTlink modified 5.3 years ago by arpa53020 • written 5.3 years ago by weihsianghuang0
gravatar for vivekbhr
5.3 years ago by
vivekbhr620 wrote:


Search for the H9 cell line and their differentiated counterparts. Most of the datasets you are probably looking for is here .

Hope this helps.

ADD COMMENTlink written 5.3 years ago by vivekbhr620

Thank you Vivek!

ADD REPLYlink written 5.3 years ago by weihsianghuang0
gravatar for arpa530
5.3 years ago by
arpa53020 wrote:

Hello!!! I am trying to find out in road map epigenomics regarding the brain cancer. So, could you please tell me which one is cancer, normal counterparts in brain cancer which is embedded in epigenomics roadmap.. Please help me to find out...

ADD COMMENTlink modified 10 months ago by RamRS30k • written 5.3 years ago by arpa53020

As far as I know road map consortium didn't collect epigenomic data from cancer. If you are referring to Polak et. al. 2015, they analysed published datasets and compared with the roadmap (normal epigenome) data.

ADD REPLYlink written 5.3 years ago by vivekbhr620
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