Question: Is r^2 equivalent to the squared pearson correlation?

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bbio •

**90**wrote:Is the r^2 between two SNPs (the measure of linkage disequilibrium between two variants) the same as the squared Pearson correlation between the two variants (encoded as 0/1/2)? In other words, to calculate the r^2 can I just take the two vectors of 0/1/2s, calculate the Pearson correlation and square the result?

Some sources seem to suggest that it is (and it would make a lot of sense to me) but I am having trouble finding a clear answer to this.

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modified 5.1 years ago
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Jean-Karim Heriche ♦

**22k**• written 5.1 years ago by bbio •**90**