I am using VEP from Ensembl to see if SNPs identified can disturb a transcription factor binding site. Based on VEP analysis you get a motif score change that is the differences between one allele and the other.
I don't understand the score I obtained. Furthermore, I don't know how to interpret differences, what is the difference to think that the SNP could have an impact on the transcription binding site? My biggest differences is -0.035.
Thanks in advance for helping me in understanding it better.